OPC Therapy

What is oropharyngeal cancer?




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  • Occurs more commonly in men than women
  • Diagnosed in adults of all ages, but most often among people in their fifties or sixties
  • Smoking and/or human papillomavirus (HPV) increase the risk of oropharyngeal cancer
  • Most oropharyngeal cancers are caused by HPV
  • Cancers caused by HPV respond better to treatment
  • Quitting smoking can help people respond better to treatment

Radiation

Surgery

Chemotherapy

Radiation, surgery and chemotherapy can be used together in different ways to treat oropharyngeal cancer

Radiation

  • High-energy x-rays
  • Delivered with a machine located outside the body
  • A radiation planning session, or "simulation", happens about 2 weeks before treatment starts
  • Your doctors will use a 3D map to help aim radiation at the cancer and protect other important structures nearby (like your voice box)

Surgery

  • Surgery removes the cancer and some of the normal-looking tissue around the cancer
  • Transoral surgery is performed through the mouth
  • A neck dissection is removal of lymph nodes from the side of the neck

Chemotherapy

  • Chemotherapy is a drug injected in a vein
  • When radiation is given, chemotherapy may be added depending on how advanced the cancer is

Possible treatment plans

Radiation-based

Radiation alone
Radiation with chemotherapy

Surgery-based

Surgery alone
Surgery with Radiation
Surgery with radiation and chemotherapy

Radiation-based

Surgery-based

  • Similar results
  • Both are standard of care
  • Not everyone is a candidate for both treatments



Learn what goes into your decision

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Adapted from the NCI's Physician Data Query